Quadruple & Octuple Screw Extruder “WDR series” Compounding Tester “ULTnano 05”

Continuous Granulation with a Twin-Screw Extruder

Quadruple and octuple layer potentials in two dimensions I: Analytical apparatus

A detailed analysis is presented of all pseudo-differential operators of orders up to 2 encountered in classical potential theory in two dimensions. Each of the operators under investigation turns out to be a sum of one or more of standard operators (second derivative, derivative of the Hilbert transform, etc.), and an integral operator with smooth kernel. This classification leads to an extrem...

Wet granulation in a twin-screw extruder: implications of screw design.

Wet granulation in twin-screw extrusion machinery is an attractive technology for the continuous processing of pharmaceuticals. The performance of this machinery is integrally tied to its screw design yet little fundamental knowledge exists in this emerging field for granulation to intelligently create, troubleshoot, and scale-up such processes. This study endeavored to systematically examine t...

Modeling Residence Time Distribution in a Twin-Screw Extruder as a Series of Ideal Steady-State Flow Reactors

Knowledge about and control of residence time distribution (RTD) is critical for determining optimal conditions in an extrusion process. In this paper, previously proposed models for RTD have been summarized and compared with the experimental data. The best-fit model was found to be a plug flow in series with a finite number of constantly stirred tank reactors having dead volume fractions. Para...

Modeling of Transport Phenomena and Melting Kinetics of Starch in a Co-Rotating Twin-Screw Extruder

A mathematical model was developed to simulate fluid flow, heat transfer, and melting kinetics of starch in a co-rotating intermeshing twin-screw extruder (TSE). The partial differential equations governing the transport phenomena of the biomaterial in the extruder were solved by a finite element scheme. For validating the model, the predicted product pressure, bulk temperature at the entrance ...